This thorough reference explores the clinical and laboratory aspects of managing methicillin-resistant Staphylococcus aureus (MRSA) infection - addressing historical features of its evolution and the extent of the current problem globally.;Written by over 15 renowned experts in the field of MRSA, Methicillin-Resistant Staphylococcus Aureus: examines epidemiologic facets of MRSA such as transmission, reservoirs, failure to detect carriers and transient carriage by staff; details MRSA detection methods including heterogenous resistance, hyper beta lactamase production, disc diffusion, broth microdilution, and automated systems; discusses restriction enzyme fingerprinting of chromosomal DNA in relation to the genetic control of putative virulence factor production; covers the pharmacokinetics, toxicity, and clinical use of agents commonly employed to treat MRSA; identifies the antimicrobials and antibiotics avialable to combat invasive MRSA infection; contrasts the North American and European approaches to treating MRSA carriers; and describes isolation and control methods and their financial implications to prevent the spread of MRSA.; Containing over 870 bibliographic references, Methicillin-Resistant Staphylococcus Aureus is for infectious disease specialists and infection control practitioners, clinical microbiologists, pharmacists, molecular biologists, hospital epidemiologists, and medical and graduate school students in these disciplines.
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