The Protein Folding Problem and Tertiary Structure Prediction

Two of the most controversial unsolved problems in molecular biology, the protein folding problem and tertiary structure prediction are detailed in this exciting look into the forefront of biotechnology. The techniques illustrated in this volume will serve as essential tools to guide the design of new protein based drugs, as well as the field of protein engineering. It is written by the world's top experts in protein folding and conformation, and includes the latest developments in lattice models, numerical methods, tertiary structure prediction, potential functions, and much more. The editors have provided a wide scope of topics and techniques, including: a review of protein folding; the dead end elimination problem; applications of neural networks in molecular sequence prediction; molecular docking of flexible ligands; knowledge-based predictions of protein structure; and future directions in this rapidly developing field. Discover the most promising new techniques for unraveling the mysteries of protein folding and structure. This collection of articles should be required reading for all molecular biologists, pharmaceutical chemists, and protein chemists in biotechnology.